How Class 3B Laser Therapy Accelerates Bone Healing
Bone injuries, from fractures to surgical repairs, often require extended recovery periods, impacting mobility and quality of life. At the Muscle and Joint Clinic, we are committed to exploring and integrating therapies that can enhance healing and reduce recovery times for our patients. One such therapy gaining significant attention is Class 3B laser therapy, also known as low-level laser therapy (LLLT) or photobiomodulation. Research reveals that this non-invasive treatment can accelerate bone healing by supporting cellular processes critical to bone repair.
Class 3B lasers operate at lower power levels (typically under 500 mW) and use wavelengths within the red and near-infrared spectrum. Unlike high-intensity lasers used for surgeries, these lasers are designed to stimulate cells without generating heat or damaging tissue. The goal of LLLT is to enhance cellular function and promote tissue repair through photochemical rather than photothermal effects.
Key Benefits of Class 3B Laser Therapy for Bone Healing
Several studies have demonstrated how Class 3B laser therapy can influence bone healing by reducing inflammation, increasing cellular energy production, and enhancing osteogenesis (the process of bone formation). Here are the primary mechanisms through which it operates:
Reducing Inflammation for an Optimal Healing Environment
Inflammation is a natural part of the healing process, but prolonged inflammation can delay recovery and lead to complications. Class 3B lasers help modulate the inflammatory response by decreasing levels of pro-inflammatory cytokines, which are proteins that signal inflammation. Research by Ebrahimi et al. (2012) found that LLLT reduces inflammation around bone injuries, allowing the bone repair process to proceed more effectively. By controlling inflammation, laser therapy creates a more conducive environment for new bone cells to develop and attach to the injured area(MDPI).
Boosting Cellular Metabolism and ATP Production
Class 3B lasers stimulate mitochondrial activity in cells, leading to an increase in ATP (adenosine triphosphate) production. ATP is the cellular energy currency, and higher ATP levels fuel cellular functions crucial to tissue repair. In their review, Berni et al. (2023) explain that Class 3B lasers, particularly those with wavelengths between 630 and 830 nm, enhance mitochondrial function by stimulating cytochrome c oxidase—a key enzyme involved in cellular respiration. This increase in ATP supports the activities of osteoblasts, the cells responsible for producing new bone tissue (Bioflex Laser).
Promoting Angiogenesis and Bone Formation
Angiogenesis, or the formation of new blood vessels, is essential for bone healing because it ensures an adequate supply of oxygen and nutrients to the injury site. The enhanced oxygen and nutrient delivery supports osteogenesis by facilitating the differentiation of mesenchymal stem cells (MSCs) into osteoblasts. Medalha et al. (2016) conducted a study on spinal cord-injured rats, finding that Class 3B laser therapy not only accelerated bone formation but also increased the expression of RUNX2, a transcription factor that regulates osteoblast differentiation and bone matrix production. These findings are encouraging for patients with compromised bone healing, as increased angiogenesis and osteogenesis can significantly speed up the recovery process (BioMed Central).
How Does Class 3B Laser Therapy Work at the Cellular Level?
Class 3B laser therapy operates through photobiomodulation, a process in which cells absorb specific wavelengths of light, leading to various beneficial biological effects:
Cytochrome c Oxidase Activation: When the laser light is absorbed by cellular chromophores (light-sensitive molecules), it activates cytochrome c oxidase in the mitochondria. This enzyme plays a crucial role in cellular respiration and increases the production of ATP. More ATP means cells have more energy to carry out repair processes, aiding in faster bone regeneration.
Reduction of Oxidative Stress: Laser therapy also decreases oxidative stress by modulating the levels of reactive oxygen species (ROS) within cells. High levels of ROS can damage cells, but appropriate modulation of ROS levels supports cellular health and function.
Release of Growth Factors: LLLT stimulates the release of growth factors like VEGF (vascular endothelial growth factor) and PDGF (platelet-derived growth factor), which are essential for tissue repair and regeneration. These growth factors support both the repair of bone tissue and the formation of new blood vessels around the injury site, which is critical for delivering the nutrients needed for bone healing.
Bringing Class 3B Laser Therapy at the Muscle and Joint Clinic
At the Muscle and Joint Clinic, we are dedicated to adopting innovative therapies that support our patients’ recovery journeys. Class 3B laser therapy is a promising addition to our suite of services, offering a safe, non-invasive approach to accelerate bone healing and reduce recovery time. By harnessing the power of light, we can stimulate the body’s natural healing mechanisms and provide our patients with effective, evidence-based treatment options.
Ebrahimi, T., Moslemi, N., Rokn, A. R., Heidari, M., Nokhbatolfoghahaie, H., & Fekrazad, R. (2012). The influence of low-intensity laser therapy on bone healing. Journal of Dentistry (Tehran), 9(4), 238–248. PMC3536459
Berni, M., Brancato, A. M., Torriani, C., Bina, V., Annunziata, S., Cornella, E., et al. (2023). The role of low-level laser therapy in bone healing: A systematic review. International Journal of Molecular Sciences, 24(8), 7094. https://doi.org/10.3390/ijms24087094
Medalha, C. C., Santos, A. L. Y. S., Veronez, S. O., Fernandes, K. R., Magri, A. M. P., & Renno, A. C. M. (2016). Low-level laser therapy accelerates bone healing in spinal cord injured rats. Journal of Photochemistry and Photobiology B: Biology, 159, 179–185. https://doi.org/10.1016/j.jphotobiol.2016.03.041